Puberty blockers
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MPs debate the puberty-blocker trial
More than 146,000 people signed a parliamentary petition set up by James Esses calling on the government to cancel...
26th March 2026
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Blocking puberty is a human-rights abuse – call off this drug trial now
Since the surprise announcement last November that a trial of puberty blockers had been approved by regulators, there has...
12th March 2026
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Letter to the Medicines and Healthcare products Regulatory Agency about Professor George
Sex Matters wrote to Lawrence Tallon, chief executive, and Professor Anthony Harnden, chair, of the MHRA, to urge them...
12th March 2026
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The puberty-blocker trial: paused but not yet stopped
The King’s College London “Pathways” clinical trial of puberty blockers has been paused because of safety and ethical concerns...
26th February 2026
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Claimant’s statement of facts and grounds in R (Bayswater Support Group and others) v HRA and Secretary of State for Health and Social Care
Statement of facts and grounds by Bayswater Support Group, Keira Bell and James Esses in their application for judicial...
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Letter to the Medicines and Healthcare products Regulatory Agency
Sex Matters wrote to the chief executive of the MHRA, Lawrence Tallon, to raise concerns about whether parents and...
25th February 2026
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Send the puberty-blocker trial back to the research ethics committee, Wes!
Last year, together with other groups, Sex Matters wrote to the secretary of state for health urging him to...
19th February 2026
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Letter to the Secretary of State for Health and Social Care
Sex Matters wrote again to the Rt Hon Wes Streeting MP about the planned puberty-blocker trial for gender-questioning children.
19th February 2026
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Reply from Secretary of State for Health on the puberty-blockers trial
Led by Rosie Duffield MP, a group of Parliamentarians wrote urgently to Wes Streeting MP on 15th December 2025...
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Letter to Secretary of State for Health on puberty-blockers trial from cross-party MPs
Led by Rosie Duffield MP, a group of Parliamentarians wrote urgently to Wes Streeting MP urging him to stop...
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The puberty-blockers trial on trial
When puberty blockers were banned for use in gender medicine in the UK, an exception was included to allow...
24th November 2025
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Letter to the Secretary of State for Health and Social Care
Sex Matters wrote to the Rt Hon Wes Streeting MP about the planned puberty-blocker trial for gender-questioning children.
24th November 2025
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Letter to the CEO of NHS England and the Secretary of State for Health and Social Care
Letter to Sir James Mackey, CEO of NHS England – copied to Wes Streeting MP, Secretary of State for...
30th April 2025
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Helen Joyce on sex, gender identity and human rights
Helen Joyce is Director of Advocacy at Sex Matters.
These are edited versions of Helen’s talks at the conferences...20th December 2024
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Puberty blockers FAQs – briefing for Parliamentarians
A two-page summary of the most frequently asked questions about puberty-suppressing drugs.
25th July 2024
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Puberty blockers – a briefing for MPs
We explain the background to the Secretary of State for Health and Social Care's decision to end the use...
23rd July 2024
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Sex and gender: a contemporary reader
Two directors of Sex Matters, Michael Biggs and Emma Hilton, have contributed chapters to Sex and Gender: A Contemporary...
18th September 2023
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Gender-questioning teenagers: puberty blockers and hormone treatment vs placebo
This technical paper adds to the literature on the treatment of gender dysphoria by using data from comparable studies...
15th December 2022